Description: This continuing education course will cover the clinically significant drug–drug interactions (DDIs) associated with oral anticancer therapies. The presentation will cover potential adverse effects of DDIs and examine key interaction pathways, including those involving CYP3A4 inhibitors and inducers, gastric acid–suppressing agents, and medications that prolong the QT interval. Strategies for identifying, preventing, and managing these interactions will be discussed to help ensure patient safety and maintain optimal therapeutic efficacy.

Microsoft Teams Webinar link to register for the live session: Register Here

Speaker: Sandi Thein Sein, PharmD, PGY2 Oncology Pharmacy Resident – Aurora St. Luke's Medical Center

Objectives: ​​ 

1. Identify oral oncology agents with high drug–drug interaction (DDI) risk and describe the key pharmacokinetic and pharmacodynamic mechanisms that contribute to potential interaction.

2. Explain how drug interactions involving CYP3A4 inhibitors and inducers influence clinical outcomes.

3. Describe the ways acid-suppressing agents interact with oral chemotherapy therapies and summarize considerations for management.

4. Explain how QT-prolonging agents interact with oral chemotherapy and outline key principles to monitor and prevent QTc prolongation.

Target Audience:​ Advocate Pharmacists, Physicians, Nurses, and other interested healthcare professionals

Disclosure:​ The planner(s) and speaker(s) have indicated that there are no relevant financial relationships with any ineligible companies to disclose. 

Materials: PDF icon Single Activity Flyer - Live-Sein.pdfPDF icon Navigating Oral Onc DDIs-Audience Slides.pdf

Pharmacist UAN: JA0006327-0000-26-001-L01-P

Session date: 
02/12/2026 - 12:00pm to 1:00pm CST
Location: 
VC-WI St Lukes Family Practice LL and Virtual via Teams
United States
See map: Google Maps
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  • 1.00 AMA PRA Category 1 Credit™
    Aurora Health Care is accredited by the Wisconsin Medical Society to provide continuing medical education for physicians. Aurora Health Care designates this activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
  • 1.00 Attendance
    Attendance Credit
    • 1.00 Approved AMA PRA Category 1 Credit™
  • 1.00 Continuing Nursing Education (CE)
    Aurora Health Care is an approved provider of continuing nursing education by the Wisconsin Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. 1.00 contact hours have been awarded to this activity by the Wisconsin Nursing Association. To receive contact hours, participants must attend the entire activity.
    • 1.00 APRN Pharmacotherapeutic Contact Hours
  • 1.00 Continuing Pharmacy Education (CPE)
    Aurora Health Care Department of Pharmacy Services is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
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