Description: This presentation will focus on differentiating between true medication-related nephrotoxicity related to piperacillin-tazobactam use, especially when combined with vancomycin. It will provide a comprehensive review of past and current literature surrounding kidney injury following piperacillin-tazobactam use in varying populations. The presentation will conclude by challenging the current status quo that piperacillin-tazobactam causes true nephrotoxicity.

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Recording: CE- You Gotta Be Kidney Me! Pseudo-nephrotoxicity of Piperacillin-tazobactam in Combination with Vancomycin-20240605_120009-Meeting Recording.mp4

Speaker:  Ayesha Alaidroos, PharmD, PGY1 Pharmacy Resident - Advocate Good Shepherd Hospital

Objectives: ​​ 

  • Differentiate between the mechanisms of drugs causing true nephrotoxicity and pseudo-nephrotoxicity
  • Recall the pharmacologic and pharmacokinetic properties of piperacillin-tazobactam and vancomycin
  • Evaluate the literature surrounding the proposition that concomitant use of piperacillin-tazobactam and vancomycin leads to nephrotoxicity
  • Formulate a nuanced approach to using combination therapy with piperacillin-tazobactam and vancomycin in patients at risk for nephrotoxicity
 
Target Audience:​ Advocate Pharmacists, Physicians, Nurses, and other interested healthcare professionals
 
Disclosure:​ The planner(s) and speaker(s) have indicated that there are no relevant financial relationships with any ineligible companies to disclose. 
Session date: 
06/05/2024 - 12:00pm to 1:00pm CDT
Location: 
Virtual Via Teams
United States
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  • 1.00 AMA PRA Category 1 Credit™
    Aurora Health Care is accredited by the Wisconsin Medical Society to provide continuing medical education for physicians. Aurora Health Care designates this activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
  • 1.00 Attendance
    Attendance Credit
    • 1.00 Approved AMA PRA Category 1 Credit™
  • 1.00 Continuing Nursing Education (CE)
    Aurora Health Care is an approved provider of continuing nursing education by the Wisconsin Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. 1.00 contact hours have been awarded to this activity by the Wisconsin Nursing Association. To receive contact hours, participants must attend the entire activity.
  • 1.00 Continuing Pharmacy Education (CPE)
    Aurora Health Care Department of Pharmacy Services is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

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